Abstract

Aqueous extract of Mimosa pudica flowers have been used for the synthesis of silver nanoparticles (MpFNp). MpFNp were characterized by UV–Visible spectroscopy, field emission scanning electron microscopy, Fourier transform infrared spectroscopy, zeta potential, energy dispersive X-ray spectroscopy, and particle size distribution by dynamic light scattering. MpFNp showed bactericidal activity at 3.125 µg/mL for E. coli (ATCC 25922), S. aureus (MTCC 1430), and 1.56 µg/mL for P. aeroginosa (ATCC 27853), 25 µg for antibiotic-resistant strains of Acinetobacter baumannii (TE1), Bacillus paramycoides (TE2), and Aeromonas veronii (TE3) isolated from tannery effluent. Antobiofilm activity was exhibited at lower concentration of MpFNp. The expression of AmpC gene was suppressed upon treatment with MpFNp. Thus, the synthesized nanoparticles can be formulated to control multidrug-resistant organisms.

摘要

含羞草花的水提取物已用于合成银纳米粒子 (MpFNp)。MpFNp 通过紫外-可见光谱、场发射扫描电子显微镜、傅里叶变换红外光谱、zeta 电位、能量色散 X 射线光谱和动态光散射的粒度分布进行表征。MpFNp显示杀菌活性在3.125微克/毫升为大肠杆菌（ATCC 25922） ，金黄色葡萄球菌（MTCC 1430），和1.56微克/毫升为P.铜绿假单胞菌感染（ATCC 27853），25微克为抗生素耐药菌株鲍曼不动杆菌(TE1)、副真菌芽孢杆菌(TE2) 和维罗单胞菌(TE3) 从制革废水中分离。在较低浓度的 MpFNp 下表现出抗生物膜活性。用 MpFNp 处理后，AmpC 基因的表达受到抑制。因此，合成的纳米颗粒可以被配制成控制多重耐药生物。