Abstract

This study aims to evaluate the effects of myo-inositol supplementation on gestational diabetes mellitus (GDM) rates and body water distribution in overweight non-obese women. 223 overweight non-obese women pregnant were randomly assigned to the treatment group (2 g of myo-inositol plus 200 µg of folic acid) or to the placebo one (200 µg of folic acid). The treatment lasted until three weeks after delivery. A tetrapolar impedance analyser was used to study body composition. The incidence of GDM was significantly reduced in the myo-inositol group compared with the placebo group. There was a significant increase in TBW, ECW and ICW values in the placebo group compared to the myo-inositol group. We have recorded a significant reduction in the overall incidence of pregnancy-induced hypertension in the myo-inositol group compared with the placebo group. Our results demonstrate the effectiveness of myo-inositol supplementation in preventing GDM in overweight non-obese pregnant women.

摘要

本研究旨在评估肌醇补充剂对超重非肥胖女性妊娠期糖尿病 (GDM) 发生率和体内水分分布的影响。223 名超重非肥胖孕妇被随机分配到治疗组（2 克肌醇加 200 微克叶酸）或安慰剂组（200 微克叶酸）。治疗持续到分娩后三周。使用四极阻抗分析仪来研究身体成分。与安慰剂组相比，肌醇组 GDM 的发生率显着降低。与肌醇组相比，安慰剂组的 TBW、ECW 和 ICW 值显着增加。我们记录到，与安慰剂组相比，肌醇组妊娠高血压的总体发病率显着降低。