Dietary fibre (DF) is implicated in gastrointestinal health of weaned piglets, either through its physiochemical properties, through modulation of gut microbiota and (or) improved gut integrity. We aimed to study the effect of DF enriched supplemental diets fed to suckling piglets (‘creep feed’) on health and performance after weaning when challenged with an enterotoxigenic E. coli (ETEC). Seventy‐two piglets originating from 28 litters had been fed four creep diets, that is a low‐fibre control (CON); a diet containing 2% long‐chain arabinoxylans from wheat (lc‐AXOS) or 5% purified cellulose (CELL) or a diet containing the high fermentable and the low‐fermentable fibre source (i.e. 2% lc‐AXOS and 5% CELL). Upon weaning, piglets were individually housed and all fed the same diet. On days 7, 8 and 9, animals received an oral dose of ETEC (5 ml containing 10⁷ to 10⁸ CFU/ml). Besides growth performance, faecal and skin scores were recorded daily. Gut permeability was assessed by urinary excretion of Co‐EDTA prior and post‐ETEC challenge. Repeated measures in time were statistically evaluated with generalized linear mixed models. We used a binominal distribution for evaluating the faecal and skin scores. Feed intake and body weight gain did not differ between treatments (p > .05). Piglets on CELL decreased gain:feed ratio in week 2 + 3 week compared to CON (p = .035). Prior to ETEC challenge, gut permeability tended to increase for lc‐AXOS (p = .092). Moreover, lc‐AXOS as main effect increased intestinal permeability before ETEC challenge (p = .013), whereas the low‐fermentable fibre lead to elevated intestinal permeability after ETEC challenge (p = .014). The incidence of diarrhoea was higher for lc‐AXOS + CELL compared with lc‐AXOS (p = .036), while skin condition was unaffected. In conclusion, neither the high fermentable nor the low‐fermentable fibre source improved post‐weaning growth or gastrointestinal health of the piglets.

中文翻译：

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在断奶前仔猪日粮中添加纤维并没有提高对断奶后产肠毒素大肠杆菌攻击的恢复能力

膳食纤维 (DF) 与断奶仔猪的胃肠道健康有关，通过其理化特性、通过调节肠道微生物群和（或）改善肠道完整性。我们的目的是研究给哺乳仔猪饲喂富含 DF 的补充日粮（“蠕动饲料”）对断奶后受到产肠毒素大肠杆菌攻击时的健康和生产性能的影响(ETEC)。来自 28 窝的 72 头仔猪喂食了四种小鸡饲料，即低纤维控制 (CON)；含有 2% 来自小麦的长链阿拉伯木聚糖 (lc-AXOS) 或 5% 纯化纤维素 (CELL) 的饮食或含有高发酵性和低发酵性纤维来源（即 2% lc-AXOS 和 5% CELL）的饮食. 断奶后，仔猪被单独圈养并饲喂相同的饮食。在第 7、8 和 9 天，动物接受口服剂量的 ETEC（5 毫升，含有 10 ⁷至 10 ⁸ CFU/毫升）。除了生长性能，每天记录粪便和皮肤评分。肠道通透性通过 ETEC 攻击前后 Co-EDTA 的尿排泄来评估。使用广义线性混合模型对时间上的重复测量进行统计评估。我们使用二项分布来评估粪便和皮肤评分。不同处理间的采食量和体重增加没有差异 ( p  > .05)。与 CON 相比，使用 CELL 的仔猪在第 2 周 + 3 周时的增重：饲料比降低 ( p  = .035)。在 ETEC 挑战之前，lc-AXOS 的肠道通透性趋于增加 ( p  = .092)。此外，在 ETEC 攻击之前，lc-AXOS 作为主要作用增加了肠道通透性（p = .013)，而低发酵纤维导致 ETEC 攻击后肠道通透性升高 ( p =  .014)。与 lc-AXOS 相比，lc-AXOS + CELL 的腹泻发生率更高 ( p  = .036)，而皮肤状况不受影响。总之，高发酵性和低发酵性纤维来源均未改善仔猪断奶后的生长或胃肠道健康。