This article deals with the synthesis of Schiff-based bis-azomethine-based ligands derived from pyridoxal and aliphatic dihydrazides and the synthesis of nickel(II) complexes C1–C4. The synthesized complexes had their structures elucidated by monocrystal X-ray diffraction and were characterized by vibrational and absorption spectroscopy. The synthesized ligands have characteristics that allow the formation of self-assembly processes, thus, the flexibility or rigidity of the coordination of organic molecules added to the orbitals of the Ni^II cation leads to the formation of helical complexes with double helix and a dinucler nickel(II) complex. Moreover, compounds was their interactions with CT-DNA and HSA absorption and emission analysis and molecular docking calculations.

本文涉及衍生自吡哆醛和脂肪族二酰肼的基于 Schiff 的双偶氮甲碱配体的合成以及镍 (II) 配合物C1 - C4的合成。合成的配合物通过单晶 X 射线衍射阐明了其结构，并通过振动和吸收光谱进行了表征。合成的配体具有允许形成自组装过程的特性，因此，添加到 Ni ^II轨道的有机分子配位的灵活性或刚性阳离子导致形成具有双螺旋和双核镍 (II) 复合物的螺旋复合物。此外，化合物是它们与 CT-DNA 和 HSA 吸收和发射分析和分子对接计算的相互作用。