An easily synthesized α-hydroxy-β-azidotetrazole scaffold was used to build a three dimensional polychromic system. Different chromophores (coumarin, BODIPY and distyryl BODIPY) were incorporated into the structure by using sequential CuAAC reactions to form a series of dyads and a triad. A computational study of the resulting arrays showed that the predominant conformations brought the substituents into close spatial proximity. The triad exhibited FRET behaviour with notably efficient energy transfer values.

中文翻译：

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通过顺序CuAAC反应合成多发色阵列

使用易于合成的α-羟基-β-叠氮唑基支架构建三维多色系统。通过使用连续的CuAAC反应，将不同的生色团（香豆素，BODIPY和二苯乙烯基BODIPY）掺入结构中，以形成一系列二元组和三元组。对所得阵列的计算研究表明，主要构象使取代基在空间上接近。该三单元组表现出具有显着有效的能量转移值的FRET行为。