Two cases of myopericytosis combined with pericytoma originating within the lung are reported. These are rare pulmonary tumors. The differential diagnosis for hemangiopericytoma and pericytic tumors with glomus elements is discussed. Both myopericytic lesions mimic other lesions, which are more commonly seen in the lung. Based on the expression of vascular growth factor receptors 2 and 3, an antiangiogenic therapy was suggested for the patient with the myopericytoma. A treatment with an angiogenesis inhibitor resulted in a regression of the tumor, but not the precursor lesion. Probably a more specific therapy using tyrosine kinase inhibitors for VEGFR2/3 might better control these myopericytic proliferations.

据报道有2例肌细胞增多症合并起源于肺内的细胞周瘤。这些是罕见的肺部肿瘤。讨论了血管球周细胞瘤和血管周肿瘤与球蛋白元素的鉴别诊断。两种肌细胞病变都模仿其他病变，在肺部更常见。根据血管生长因子受体2和3的表达，建议对肌细胞瘤患者进行抗血管生成治疗。用血管生成抑制剂治疗可导致肿瘤消退，但不能消退前体病变。对于VEGFR2 / 3，使用酪氨酸激酶抑制剂进行更具体的治疗可能可以更好地控制这些肌细胞增殖。