This appraisal is comprised of the inflammatory studies that have been conducted on Clinacanthus nutans, Acanthus ebracteatus, and Barleria lupulina. The review aims to provide a comprehensive evaluation of the supporting and contradictory evidence on each plants’ anti-inflammatory properties, whilst addressing the gaps in the current literature. The databases used to obtain relevant studies were Google Scholar, ResearchGate, PubMed and Nusearch (University of Nottingham). A total of 13 articles were selected for this review. A. ebracteatus was found to suppress neutrophil migration and weakly inhibits chronic inflammatory cytokines. Furthermore, B. lupulina and C. nutans were shown to possess very similar anti-inflammatory properties. The studies on C. nutans indicated that its anti-inflammatory effect is strongly related to the inhibition of toll-like receptor 4 (TLR4). Moreover, several phytoconstituents isolated from B. lupulina were shown to activate the anti-inflammatory Nrf2 pathway. Overall, all the studies have provided evidence to support the use of these plants as anti-inflammatory herbal remedies. However, their exact mechanism of action and the responsible phytoconstituents are yet to be established.

该评估是由已经上进行炎症研究Clinacanthus穗披碱草，小花老鼠簕，和花叶假杜鹃。该综述旨在针对每种植物的抗炎特性提供支持和矛盾证据的全面评估，同时解决当前文献中的空白。用于获得相关研究的数据库是Google Scholar，ResearchGate，PubMed和Nusearch（诺丁汉大学）。共有13篇文章被选中进行本次综述。发现ebracteatus抑制中性粒细胞迁移，并弱抑制慢性炎症细胞因子。此外，棉铃虫和坚果被证明具有非常相似的抗炎特性。对坚果梭菌的研究表明，其抗炎作用与抑制toll样受体4（TLR4）密切相关。此外，从分离的几个phytoconstituents B.天蓝苜蓿显示出激活抗炎途径Nrf2的。总体而言，所有研究都提供了证据支持将这些植物用作抗炎草药。但是，它们的确切作用机理和负责任的植物成分尚未确定。