A new type of multifunctional metal-organic frameworks (MOFs) was synthesized by encapsulating gold nanoparticles (AuNPs) into the Cu-hemin MOFs, and first applied to an electrochemical sensor to detect catechol (CT) with the aid of electrochemically reduced graphene oxide (ERGO) for signal amplification. First, ERGO was electrochemically deposited on a bare glass carbon electrode (GCE), followed by casting Cu-hemin MOFs on an ERGO-modified electrode, and then growing AuNPs in situ on Cu-hemin MOFs/ERGO/GCE by electrochemical deposition. Cyclic voltammetry (CV), scanning electron microscopy (SEM) and current–time ([Formula: see text]–[Formula: see text] were utilized to characterize the electrochemical performance and surface characteristics of the as-prepared sensor. The results demonstrated that Cu-hemin MOFs have not only been a matrix to avoid the aggregation of AuNPs but also an ideal loading platform for the adsorption of CT due to its large surface area and porosity. In addition, the ERGO also has the advantage of fast electron transfer, which can make synergy with AuNPs@Cu-hemin MOFs nanocomposites to amplify the electrical signal. The AuNPs/Cu-hemin MOFs/ERGO/GCE exhibited an excellent electrocatalytic activity with increased electrochemical signals towards the oxidation of CT. Under the optimum experimental conditions, the sensor shows a wide linear relationship over the range of [Formula: see text][Formula: see text]M to [Formula: see text][Formula: see text]M with a detection limit of [Formula: see text][Formula: see text]M. Moreover, the sensor presented the good reproducibility and the excellent anti-interference performance. This work would broaden the application of MOFs material in constructing more novel electrochemical sensing platform.

中文翻译：

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将金纳米颗粒多功能封装到铜-血红素/金属-有机框架中，用于石墨烯基电极上的儿茶酚电化学检测

通过将金纳米粒子 (AuNPs) 包裹在 Cu-hemin MOFs 中合成了一种新型多功能金属有机框架 (MOFs)，并首次应用于电化学传感器，借助电化学还原氧化石墨烯检测邻苯二酚 (CT)。 ERGO) 用于信号放大。首先，将ERGO电化学沉积在裸玻璃碳电极（GCE）上，然后将Cu-hemin MOFs浇铸在ERGO修饰电极上，然后通过电化学沉积在Cu-hemin MOFs/ERGO/GCE上原位生长AuNPs。循环伏安法（CV）、扫描电子显微镜（SEM）和电流-时间（[公式：见正文]-[公式：见正文]用于表征所制备传感器的电化学性能和表面特性。结果表明，Cu-hemin MOFs不仅是避免AuNPs聚集的基质，而且由于其大的表面积和孔隙率，它也是吸附CT的理想负载平台。此外，ERGO还具有快速电子转移的优势，可与AuNPs@Cu-hemin MOFs纳米复合材料协同放大电信号。AuNPs/Cu-hemin MOFs/ERGO/GCE 表现出优异的电催化活性，并增加了对 CT 氧化的电化学信号。在最佳实验条件下，传感器在[公式：见正文][公式：见正文]M到[公式：见正文][公式：见正文]M的范围内表现出较宽的线性关系，检测限为[公式：见正文][公式：见正文]M．而且，该传感器具有良好的重现性和优异的抗干扰性能。这项工作将拓宽 MOFs 材料在构建更新颖的电化学传感平台中的应用。