The synthesis and X-ray structure of a novel glycoluril derivative are described. The crystal of the glycoluril derivative is obtained by slow evaporation in a refrigerator at about 5 °C. X-ray crystallographic analysis revealed that the compound crystallized in an unusual as conformation instead of the usual clip-shaped aa conformation. Structural analysis shows that the solvation effect, hydrogen bonding, and space-occupying effect influenced the crystallization conformation of the derivative. The X-ray crystallographic analysis in this work provides additional crystallographic evidence of the as conformation of the 3U glycoluril derivative and shows the effect of solvent water on the conformational behavior.

描述了新型甘脲衍生物的合成和X射线结构。通过在约5℃的冰箱中缓慢蒸发获得甘脲衍生物的晶体。X-射线结晶分析表明，该化合物在一个不寻常的结晶作为构象而不是通常的夹子状AA构象。结构分析表明，溶剂化作用，氢键作用和空间占据作用影响了衍生物的结晶构象。在这项工作中的X射线晶体分析提供了额外的结晶证据为的3U甘脲衍生物和示出了的溶剂中的水的构象行为的影响构象。