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Characterization of defined sulfated heparin‐like oligosaccharides by electrospray ionization ion trap mass spectrometry
Journal of Mass Spectrometry ( IF 1.9 ) Pub Date : 2020-11-25 , DOI: 10.1002/jms.4692
Katharina Lemmnitzer 1 , Sebastian Köhling 2 , Joanna Freyse 2 , Jörg Rademann 2 , Jürgen Schiller 1
Affiliation  

Glycosaminoglycans (GAG) as long, unbranched polysaccharides are major components of the extracellular matrix. Many studies provided additional evidence of a specific binding between mediators and sulfated GAG, at which the sulfation code—which means the number and positions of sulfate groups along the polysaccharide chain—plays an important role.

中文翻译:

通过电喷雾电离离子阱质谱法表征定义的硫酸化肝素样寡糖

糖胺聚糖 (GAG) 作为长而无支链的多糖是细胞外基质的主要成分。许多研究提供了介质与硫酸化 GAG 之间特异性结合的额外证据,其中硫酸化代码(即多糖链上硫酸盐基团的数量和位置)起着重要作用。
更新日期:2021-01-08
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