Solar radiation is an essential input in the design and operation of many engineering systems. However, access to high-resolution data (hourly or sub-hourly) is usually limited, especially in developing countries, either due to its unavailability or expensive costs. A novel data-driven approach is proposed to predict the hourly global irradiation profiles from the cheaper and more likely available records of daily global irradiation. The proposed approach is based on a prior categorization of hourly observations using the K-means clustering algorithm, followed by non-parametric function approximation using the multi-layered perceptron artificial neural network. This approach is applied to measured data (130000 data points) at six locations in the North African Sahara, and the developed models are benchmarked against all existing parametric models in the literature. The artificial neural network-based models outperformed all existing models, with maximum and minimum coefficients of determination of 0.960 and 0.930, respectively. The non-parametric models also captured the true asymmetric profiles of hourly irradiation with enhanced distributions of the residuals. Hence, the suggested models can be used to generate synthetic hourly data for multiple applications, most notably for building energy simulations and scheduling the operation of power generation systems.