Amyloid-β precursor protein (APP) is overshadowed by its degradation product, the Alzheimer protein Aβ. Lee et al. now find a role for the APP family in neuronal excitability, synaptic plasticity, and memory in adulthood, despite the lack of requirement for neuronal survival.

中文翻译：

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APP家族在大脑中做什么？

淀粉样蛋白 β 前体蛋白 (APP) 被其降解产物阿尔茨海默蛋白 Aβ 所掩盖。李等人。现在发现 APP 家族在神经元兴奋性、突触可塑性和成年期记忆中的作用，尽管缺乏神经元存活的要求。