Abstract In this study, photocatalytic titanium dioxide (TiO2) nanoparticles were introduced to polymethyl methacrylate (PMMA) to obtain PMMA/TiO2 nanocomposites, which were subsequently patterned with a shark-skin structure via polydimethylsiloxane (PDMS) transfer replication. The results showed that, contrary to the flat PMMA/TiO2 nanocomposites, the shark-skin-patterned PMMA/TiO2 nanocomposites prevented the development of biofilms for up to 2 weeks because of the synergistic effects of their photocatalytic, antibacterial, and structural properties. This study provides a practical approach to inhibit biofilm formation.

中文翻译：

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具有鲨鱼皮结构的聚（甲基丙烯酸甲酯）/二氧化钛（PMMA/TiO2）纳米复合材料可防止生物膜形成

摘要 在本研究中，将光催化二氧化钛 (TiO2) 纳米粒子引入聚甲基丙烯酸甲酯 (PMMA) 中以获得 PMMA/TiO2 纳米复合材料，随后通过聚二甲基硅氧烷 (PDMS) 转移复制将其图案化为鲨鱼皮结构。结果表明，与扁平的 PMMA/TiO2 纳米复合材料相反，鲨鱼皮图案的 PMMA/TiO2 纳米复合材料由于其光催化、抗菌和结构特性的协同作用，可阻止生物膜的形成长达 2 周。该研究提供了一种抑制生物膜形成的实用方法。