There is a lack of population based studies of autoimmune encephalitis (AE) in Latin American countries, especially in Colombia. The aim of this study is to characterize patients with AE managed in three centers in Bogotá-Colombia, emphasizing on antibody profile. We conducted a retrospective case-series study, including 9 patients. The most prevalent antibody found was NMDAR, followed by LGI1. Some distinguishing features included: faciobrachial dystonia and hyponatremia in LGI1, a younger age and good outcome in NMDAR, a notable response to steroids in anti TPO-Thyroglobulin, a cerebellar syndrome associated with Anti-Yo, and epilepsy with insomnia in CASPR2.

中文翻译：

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脑炎的多重面孔：哥伦比亚波哥大一系列自身免疫性脑炎病例中的抗体特征


拉丁美洲国家，特别是哥伦比亚，缺乏针对自身免疫性脑炎（AE）的人群研究。本研究的目的是描述哥伦比亚波哥大三个中心治疗的 AE 患者的特征，重点是抗体谱。我们进行了一项回顾性病例系列研究，包括 9 名患者。最常见的抗体是 NMDAR，其次是 LGI1。一些显着特征包括：LGI1 中的面臂肌张力障碍和低钠血症、NMDAR 中的年龄较小和良好的结果、抗 TPO-甲状腺球蛋白中对类固醇的显着反应、与 Anti-Yo 相关的小脑综合征以及 CASPR2 中的癫痫伴失眠。