Abstract

Ionized products of desorption of thiosemicarbazides from a steel target surface before and after deposition of solid solutions of thiosemicarbazides in organic matrices (nicotinic acid, α-cyano-4-hydroxycinnamic acid, 2,5-dihydroxybenzoic acid, and dithranol) onto it have been studied by mass spectrometry. 2,5-Dihydroxybenzoic acid has been revealed to be a universal matrix for studying the synthesized thiosemicarbazides under the conditions of matrix-assisted laser desorption/ionization. Its use leads to a 100-fold decrease in the detection limit of thiosemicarbazides as compared with α-cyano-4-hydroxycinnamic acid. Investigations of the decomposition of metastable protonated thiosemicarbazide molecules accelerated in the ion-source region have resulted in suggesting the mechanisms of their fragmentation and ionization.

中文翻译：

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硫代氨基脲的激光解吸和电离

摘要

硫代氨基甲酸酯在有机基质（烟酸，α-氰基-4-羟基肉桂酸，2,5-二羟基苯甲酸和二苏醇）中固溶体沉积前后的离子化产物已从钢靶表面脱附。通过质谱研究。已经发现2，5-二羟基苯甲酸是用于在基质辅助的激光解吸/电离条件下研究合成的硫代氨基脲的通用基质。与α-氰基-4-羟基肉桂酸相比，它的使用导致硫代氨基脲的检出限降低了100倍。对在离子源区中加速的亚稳态质子化硫代氨基脲分子分解的研究表明，它们的断裂和电离机理已经提出。