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Knockout of miR-21-5p alleviates cartilage matrix degradation by targeting Gdf5 in temporomandibular joint osteoarthritis.
Bone & Joint Research ( IF 4.7 ) Pub Date : 2020-11-25 , DOI: 10.1302/2046-3758.910.bjr-2020-0140.r1
Aobo Zhang 1 , Shixing Ma 1 , Lingyu Yuan 1 , Shichao Wu 2 , Shaopeng Liu 1 , Xiang Wei 1 , Lei Chen 1 , Chuan Ma 1 , Huaqiang Zhao 1
Affiliation  

The study aimed to determine whether the microRNA miR21-5p (MiR21) mediates temporomandibular joint osteoarthritis (TMJ-OA) by targeting growth differentiation factor 5 (Gdf5).

中文翻译:

敲除 miR-21-5p 可通过靶向 Gdf5 减轻颞下颌关节骨关节炎中的软骨基质降解。

该研究旨在确定 microRNA miR21-5p (MiR21) 是否通过靶向生长分化因子 5 (Gdf5) 介导颞下颌关节骨关节炎 (TMJ-OA)。
更新日期:2020-11-26
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