Background To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make a valuable contribution as they are not associated with cancellation artifacts and include also the peripheral visual field. Objective To investigate if occipital repetitive transcranial magnetic stimulation (rTMS) can induce mfVEP changes. Methods 18 healthy participants were included in a single-blind crossover-study receiving sessions of excitatory, occipital 10 Hz rTMS and sham stimulation. MfVEP was performed before and after each rTMS session and changes in amplitude and latency between both sessions were compared using generalized estimation equation models. Results There was no significant difference in amplitude or latency between verum and sham group. Conclusion We conclude that occipital 10 Hz rTMS has no effect on mfVEP measures, which is in line with previous studies using full field VEP.

中文翻译：

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枕部重复经颅磁刺激不影响多焦视觉诱发电位

背景 为了确定视觉皮层皮质可塑性的机制并量化其重要性，需要使用敏感参数。在这种情况下，多焦点视觉诱发电位 (mfVEP) 可以做出有价值的贡献，因为它们与消除伪影无关，还包括周边视野。目的探讨枕部重复经颅磁刺激（rTMS）是否能诱发mfVEP变化。方法 18 名健康参与者被包括在接受兴奋性、枕骨 10 Hz rTMS 和假刺激的单盲交叉研究中。在每个 rTMS 会话之前和之后执行 MfVEP，并使用广义估计方程模型比较两个会话之间的振幅和潜伏期变化。结果真假组与假手术组的波幅或潜伏期无显着差异。结论 我们得出结论，枕骨 10 Hz rTMS 对 mfVEP 测量没有影响，这与之前使用全场 VEP 的研究一致。