Based on a large study conducted on wild great ape fecal samples collected in regions of Gabon where previous human outbreaks of Ebola virus disease have occurred between 1994 and 2002, we provide evidence for prevalence of Zaire ebolavirus (EBOV)-specific antibodies of 3.9% (immunoglobulin G (IgG)) and 3.5% (immunoglobulin M (IgM)) in chimpanzees and 8.8% (IgG) and 2.4% (IgM) in gorillas. Importantly, we observed a high local prevalence (31.2%) of anti-EBOV IgG antibodies in gorilla samples. This high local rate of positivity among wild great apes raises the question of a spatially and temporally localized increase in EBOV exposure risk and the role that can be played by these animals as sentinels of the virus’s spread or reemergence in a given area.

中文翻译：

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加蓬大猿粪便样本中埃博拉病毒抗体的检测

根据对在加蓬地区收集的野生大猿粪便样本进行的一项大型研究，在该地区以前人类曾在1994年至2002年之间爆发过埃博拉病毒病的爆发，我们为扎伊尔埃博拉病毒（EBOV）特异性抗体的流行率为3.9％提供了证据（黑猩猩的免疫球蛋白G（IgG）和3.5％（免疫球蛋白M（IgM）），大猩猩的免疫球蛋白G（IgG）和3.5％（IgG）和2.4％（IgM）。重要的是，我们在大猩猩样品中观察到了较高的局部抗EBOV IgG抗体患病率（31.2％）。野生大猿在当地的这种高阳性率提出了这样一个问题，即EBOV暴露风险在空间和时间上局部增加，以及这些动物作为病毒在给定区域中传播或重新出现的前哨动物所起的作用。