Cadmium (Cd) is a toxic heavy metal that when absorbed into the body causes nephrotoxicity and effects in other tissues.Anatomical barrier tissues are tissues that prevent the entry of pathogens and include skin, mucus membranes and the immune system. The adverse effects of Cd-induced immune cell's activity are the most extensively studied in the kidneys and the liver There are though fewer data relating the effect of this metal on the other tissues, particularly in those in which cells of the immune system form local circuits of tissue defense, maintaining immune-mediated homeostasis. In this work, data on the direct and indirect effects of Cd on anatomical barrier tissue of inner and outer body surfaces (the lungs, gut, reproductive organs, and skin) were summarized.

中文翻译：

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解剖屏障组织的镉和免疫介导的稳态

镉 (Cd) 是一种有毒重金属，被人体吸收后会引起肾毒性并影响其他组织。解剖屏障组织是防止病原体进入的组织，包括皮肤、黏膜和免疫系统。Cd 诱导的免疫细胞活性的不利影响在肾脏和肝脏中得到了最广泛的研究。尽管有关这种金属对其他组织的影响的数据较少，特别是在那些免疫系统细胞形成局部回路的组织中组织防御，维持免疫介导的体内平衡。在这项工作中，总结了 Cd 对身体内外表面（肺、肠道、生殖器官和皮肤）解剖屏障组织的直接和间接影响的数据。