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Neurobrucellosis due to Brucella ceti ST26 in Three Sowerby's Beaked Whales (Mesoplodon bidens)
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2020-11-24 , DOI: 10.1016/j.jcpa.2020.10.005
Nicholas J Davison 1 , Andrew Brownlow 1 , Mariel Ten Doeschate 1 , Emma-Jane Dale 2 , Geoffrey Foster 1 , Jakub Muchowski 2 , Lorraine L Perrett 2 , Mara Rocchi 3 , Adrian M Whatmore 2 , Mark P Dagleish 3
Affiliation  

Fatal meningoencephalitis due to Brucella ceti infection has been described in striped dolphins (Stenella coeruleoalba), Atlantic white-sided dolphins (Lagenorhynchus acutus), short-beaked common dolphins (Delphinus delphis) and long-finned pilot whales (Globicephala melas), which are all within the family Delphinidae. We report B. ceti-associated neurobrucellosis in three juvenile male Sowerby's beaked whales (Mesoplodon bidens) that all had typical lesions of lymphocytic meningoencephalitis, which increased in severity from rostral to caudal regions of the brain. In two cases there was loss of ependymal cells lining the cerebral ventricular system, with large numbers of lymphocytes in the underlying neuropil. This finding suggests that B. ceti gains access to, and multiplies in, the cerebrospinal fluid, and confirms that this is the sample of choice for bacteriological recovery of the causative organism. These findings expand the increasing range of cetaceans susceptible to neurobrucellosis to members of the family Ziphiidae.



中文翻译:

三只苏尔比喙鲸(Mesoplodon bidens)中由鲸豚布鲁氏菌 ST26 引起的神经布鲁氏菌病

已在条纹海豚 ( Stenella coeruleoalba )、大西洋白边海豚 ( Lagenorhynchus acutus )、短喙普通海豚 ( Delphinus delphis ) 和长鳍领航鲸 ( Globicephala ) 中描述了由于鲸豚布鲁氏菌感染引起的致命脑膜脑炎都属于海豚科。我们报告B. CETI机相关neurobrucellosis三个少年雄索尔的喙鲸(Mesoplodon鬼针) 所有人都有淋巴细胞性脑膜脑炎的典型病变,其严重程度从大脑的头端到尾端区域增加。在两个病例中,脑室系统内衬室管膜细胞丢失,下方神经纤维网中有大量淋巴细胞。这一发现表明B. ceti获得并在脑脊液中繁殖,并证实这是致病生物细菌学恢复的首选样本。这些发现将易患神经布鲁氏菌病的鲸目动物的范围扩大到 Ziphiidae 科的成员。

更新日期:2020-11-25
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