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Nanoenzymes in disease diagnosis and therapy
Chemical Communications ( IF 4.9 ) Pub Date : 2020-11-11 , DOI: 10.1039/d0cc05427e
Zhengze Yu 1, 2, 3, 4, 5 , Ruxin Lou 1, 2, 3, 4, 5 , Wei Pan 1, 2, 3, 4, 5 , Na Li 1, 2, 3, 4, 5 , Bo Tang 1, 2, 3, 4, 5
Affiliation  

Nanoenzymes, as a new generation of artificial enzymes with highly effective enzyme-like properties, have come into focus and have achieved great progress. Considering the enormous potential of nanoenzymes in the field of disease diagnosis and treatment, such as biological detection, anti-inflammatory, anti-oxidative damage and cancer treatments, etc., we firstly summarize the wide range of bio-applications of different nanoenzymes in these fields. In this review, we discuss the factors influencing the properties of nanoenzymes such as pH and temperature, surface modification and doping of other elements. In addition, we introduce five kinds of nanoenzymes and their bio-applications in various diseases. The current review will make researchers better understand the current state of the development of nanoenzymes and may be beneficial for new breakthroughs.

中文翻译:

纳米酶在疾病的诊断和治疗中

纳米酶作为具有高效酶样性质的新一代人工酶已成为人们关注的焦点,并取得了长足的进步。考虑到纳米酶在疾病诊断和治疗领域的巨大潜力,例如生物检测,抗炎,抗氧化损伤和癌症治疗等。,我们首先总结这些领域中不同纳米酶的广泛生物应用。在这篇综述中,我们讨论了影响纳米酶特性的因素,例如pH和温度,表面改性和其他元素的掺杂。此外,我们介绍了五种纳米酶及其在各种疾病中的生物应用。当前的综述将使研究人员更好地了解纳米酶的发展现状,并可能对新的突破有所帮助。
更新日期:2020-11-25
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