Bronchiectasis, which is an abnormal and irreversible dilation of one or several bronchial segments, causes significant morbidity and impaired quality of life to patients, mainly as the result of recurrent and chronic respiratory infections. Staphylococcus aureus is a microorganism known for its high infectious potential related to the production of molecules with great pathogenic power, such as enzymes, toxins, adhesins, and biofilm, which determine the degree of severity of systemic symptoms and can induce exacerbated immune response. This review highlighted the clinical significance of S. aureus colonization/infection in bronchiectasis patients, since little is known about it, despite its increasing frequency of isolation and potential serious morbidity.

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金黄色葡萄球菌及其对支气管扩张预后的影响

支气管扩张症是一个或几个支气管节段的异常和不可逆扩张，主要是由于反复和慢性呼吸道感染导致患者发病率高和生活质量下降。金黄色葡萄球菌是一种微生物，因其与产生具有强大致病力的分子（如酶、毒素、粘附素和生物膜）相关的高感染潜力而闻名，这些分子决定了全身症状的严重程度，并可诱导加剧的免疫反应。本综述强调了金黄色葡萄球菌定植/感染在支气管扩张患者中的临床意义，因为对其知之甚少，尽管其分离频率和潜在的严重发病率不断增加。