当前位置: X-MOL 学术SynOpen › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Iodine-Mediated Facile One-Pot Access to N-Aryl-2-benzoxazolamines
SynOpen ( IF 2.0 ) Pub Date : 2020-11-24 , DOI: 10.1055/s-0040-1705982
Shinji Tanimori , Haruna Nariki , Takuya Miyamura , Daiki Matsui , Motohiro Sonoda

Facile, iodine-mediated access to N-aryl-2-benzoxazolamines has been achieved in a one-pot manner under mild reaction conditions. Reaction of 2-aminophenols and aryl isothiocyanates afforded N-aryl-2-benzoxazolamines in the presence of molecular iodine and pyridine in tetrahydrofuran at room temperature in moderate to excellent yields.



中文翻译:

碘介导的一锅法获得N-芳基-2-苯并恶唑胺

在温和的反应条件下,以单锅方式实现了碘介导的N-芳基-2-苯并恶唑胺的便捷连接。在室温下,在四氢呋喃中,在存在分子碘和吡啶的条件下,在氨基碘和吡啶存在下,N-芳基-2-苯并恶唑胺与2-氨基酚和芳基异硫氰酸酯反应,得到中等至极好的收率。

更新日期:2020-11-25
down
wechat
bug