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Porphyromonas gingivalis and Lactobacillus rhamnosus GG regulate the Th17/Treg balance in colitis via TLR4 and TLR2
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2020-11-24 , DOI: 10.1002/cti2.1213
Lu Jia 1 , Ruiqing Wu 2 , Nannan Han 1 , Jingfei Fu 1 , Zhenhua Luo 1 , Lijia Guo 3 , Yingying Su 2 , Juan Du 1 , Yi Liu 1
Affiliation  

CD4+ T cells are the key to many immune–inflammatory diseases mediated by microbial disorders, especially inflammatory bowel disease (IBD). The purpose of this study was to explore how pathogenic and probiotic bacteria directly affect the T helper (Th)17 and T regulatory (Treg) cell balance among CD4+ T cells to regulate inflammation.

中文翻译:

牙龈卟啉单胞菌和鼠李糖乳杆菌GG通过TLR4和TLR2调节结肠炎Th17/Treg平衡

CD4 + T 细胞是许多由微生物疾病介导的免疫炎症疾病的关键,尤其是炎症性肠病 (IBD)。本研究的目的是探讨致病菌和益生菌如何直接影响 CD4 + T 细胞之间的 T 辅助 (Th)17 和 T 调节 (Treg) 细胞平衡以调节炎症。
更新日期:2020-11-25
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