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Cover Feature: Nontoxic Cobalt(III) Schiff Base Complexes with Broad‐Spectrum Antifungal Activity (Chem. Eur. J. 6/2021)
Chemistry - A European Journal ( IF 3.9 ) Pub Date : 2020-11-24 , DOI: 10.1002/chem.202004912
Angelo Frei 1 , A. Paden King 2 , Gabrielle J. Lowe 1 , Amy K. Cain 3 , Francesca L. Short 3 , Hue Dinh 3, 4 , Alysha G. Elliott 1 , Johannes Zuegg 1 , Justin J. Wilson 2 , Mark A. T. Blaskovich 1
Affiliation  

New cobalt(III) Schiff base complexes with antifungal activity against a range of fungal pathogens are reported in this work. In addition, these compounds showed no cytotoxicity against mammalian cells and no toxicity in vivo against Galleria mellonella at high concentrations. More information can be found in the Full Paper by A. Frei, M. A. T. Blaskovich, et al. on page 2021.
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中文翻译:

封面人物:具有广谱抗真菌活性的无毒钴(III)希夫碱配合物(Chem。Eur。J. 6/2021)

在这项工作中报道了具有对多种真菌病原体具有抗真菌活性的新型钴(III)席夫碱复合物。另外,这些化合物在高浓度下对哺乳动物细胞没有细胞毒性,在体内也没有对梅勒菌廊的毒性。有关更多信息,请参见A. Frei,M.A。T. Blaskovich等人的《全文》。在2021页。
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更新日期:2021-01-27
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