How To Quantify a Genetic Firewall? A Polarity‐Based Metric for Genetic Code Engineering,ChemBioChem

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How To Quantify a Genetic Firewall? A Polarity‐Based Metric for Genetic Code Engineering
ChemBioChem ( IF 2.6 ) Pub Date : 2020-11-24 , DOI: 10.1002/cbic.202000758
Markus Schmidt ₁ , Vladimir Kubyshkin ₂

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Quantifying the distance: If two organisms operate under different genetic codes, how likely is that they could still properly interpret each other's genes? We introduce a versatile metric to quantify the distance between the different genetic codes. It can calculate the distance (dissimilarity) between genetic codes and can be applied with the 20 canonical but also noncanonical amino acids.

中文翻译：

如何量化基因防火墙？遗传密码工程的基于极性的度量

量化距离：如果两个生物体在不同的遗传密码下运作，它们仍然能够正确解释彼此基因的可能性有多大？我们引入了一种通用指标来量化不同遗传密码之间的距离。它可以计算遗传密码之间的距离（相异性），并且可以应用于 20 种规范氨基酸和非规范氨基酸。

更新日期：2020-11-24

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