Biosynthetic Intermediate Probes for Visualizing and Identifying the Biosynthetic Enzymes of Plant Metabolites,ChemBioChem

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Biosynthetic Intermediate Probes for Visualizing and Identifying the Biosynthetic Enzymes of Plant Metabolites
ChemBioChem ( IF 2.6 ) Pub Date : 2020-11-24 , DOI: 10.1002/cbic.202000530
Lei Gao ₁ , Xiaoguang Lei ₁

Affiliation

See what‘s missing: Biosynthetic study of plant metabolites paves the way for manufacturing plant‐derived drugs by synthetic biology. However, identifying any missing enzymes in a plant metabolic pathway is a formidable challenge. Biosynthetic intermediate probes make potentially useful tools to resolve the challenge by visualizing biosynthetic enzymes to facilitate transcriptome analysis or chemical proteomics approaches for identifying the biosynthetic enzymes.

中文翻译：

用于可视化和识别植物代谢物生物合成酶的生物合成中间体探针

看看缺少什么：植物代谢物的生物合成研究为通过合成生物学制造植物衍生药物铺平了道路。然而，识别植物代谢途径中任何缺失的酶是一项艰巨的挑战。生物合成中间探针通过可视化生物合成酶来促进转录组分析或化学蛋白质组学方法来识别生物合成酶，从而成为解决挑战的潜在有用工具。

更新日期：2020-11-24

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