Disease Prediction: Prediction of Chronic Inflammation for Inhaled Particles: the Impact of Material Cycling and Quarantining in the Lung Epithelium (Adv. Mater. 47/2020)
Advanced Materials
(
IF27.4
)
Pub Date : 2020-11-24, DOI: 10.1002/adma.202070353
Hana Kokot
1,
2
,
Boštjan Kokot
1,
3
,
Aleksandar Sebastijanović
1,
2
,
Carola Voss
4
,
Rok Podlipec
1,
5
,
Patrycja Zawilska
1
,
Trine Berthing
6
,
Carolina Ballester‐López
4
,
Pernille Høgh Danielsen
6
,
Claudia Contini
7
,
Mikhail Ivanov
8
,
Ana Krišelj
1
,
Petra Čotar
1,
9
,
Qiaoxia Zhou
4,
10
,
Jessica Ponti
11
,
Vadim Zhernovkov
12
,
Matthew Schneemilch
7
,
Zahra Doumandji
13
,
Mojca Pušnik
14
,
Polona Umek
1
,
Stane Pajk
1,
14
,
Olivier Joubert
13
,
Otmar Schmid
4
,
Iztok Urbančič
1
,
Martin Irmler
15
,
Johannes Beckers
15,
16,
17
,
Vladimir Lobaskin
18
,
Sabina Halappanavar
19
,
Nick Quirke
7
,
Alexander P. Lyubartsev
8
,
Ulla Vogel
6
,
Tilen Koklič
1
,
Tobias Stoeger
4
,
Janez Štrancar
1
Affiliation
Department of Condensed Matter Physics Jožef Stefan Institute Ljubljana 1000 Slovenia
Jožef Stefan International Postgraduate School Ljubljana 1000 Slovenia
Faculty of Natural Sciences and Mathematics University of Maribor Maribor 2000 Slovenia
Institute of Lung Biology and Disease Helmholtz Zentrum München 85764 Neuherberg Germany
Ion Beam Center Helmholtz‐Zentrum Dresden‐Rossendorf e.V. 01328 Dresden Germany
National Research Centre for the Working Environment Copenhagen Ø 2100 Denmark
Department of Chemistry Molecular Sciences Research Hub Imperial College London London W12 0BZ UK
Department of Materials and Environmental Chemistry Stockholm University Stockholm SE‐10691 Sweden
Faculty of Mathematics and Physics University of Ljubljana Ljubljana 1000 Slovenia
Department of Forensic Pathology Sichuan University Chengdu 610065 China
European Commission Joint Research Centre (JRC) Ispra 21027 Italy
Systems Biology Ireland School of Medicine University College Dublin Belfield Dublin 4 Ireland
Institut Jean Lamour, UMR CNRS 7198 Université de Lorraine CNRS, IJL Nancy F‐54000 France
Faculty of Pharmacy University of Ljubljana Ljubljana 1000 Slovenia
Institute of Experimental Genetics Helmholtz Zentrum München 85764 Neuherberg Germany
German Center for Diabetes Research (DZD) 85764 Neuherberg Germany
Chair of Experimental Genetics, Center of Life and Food Sciences, Weihenstephan Technische Universität München 85354 Freising Germany
School of Physics University College Dublin Belfield Dublin 4 Ireland
Environmental Health Science and Research Bureau Health Canada Ottawa K1Y 0M1 Canada
The prediction of diseases associated with nanomaterials is currently hampered by an incomplete understanding of the underlying mechanisms. Newly discovered nanomaterial quarantining and counteracting nanomaterial cycling fill that gap allowing Tilen Koklič, Tobias Stoeger, Janez Štrancar, and co‐workers to incorporate these main modes of cellular response into a mechanistic model and predict in vivo inflammation solely on animal‐free in vitro tests, as described in article number 2003913.
京公网安备 11010802027423号