Degradation of tetracycline (TTC) with a heterogeneous Fenton-like pyrite/H₂O₂ process by pyrite from mine waste as a mineral catalyst was investigated. The study focused on identifying the main oxidizing agents and degradation mechanisms along with operational variables including solution pH, pyrite and H₂O₂ concentration, contact time, solution temperature, and initial TTC concentration. Catalyst characterization tests revealed that pyrite is a mesoporous powder with a high degree of FeS₂ purity. Radical scavenger tests demonstrated that ^•OH was the main oxidizing agent generated by both solution and surface phase reactions. During the pyrite/H₂O₂ process, more than 85% of TTC was mineralized in 60 min and the maximum TTC removal was attained in the solution at an acidic pH value (4.1). The most abundant transformation products of TTC, formed by the attack of ^•OH radicals, were simple chain carboxylic acids. Cultured cells of human embryonic kidney (HEK) were used for the cytotoxicity assessment of raw and pyrite/H₂O₂ treated TTC solutions. The results illustrated that the viability of HEK cells was enhanced considerably after treating TTC solutions under optimal conditions. Accordingly, pyrite originating from mine waste is a practically effective and cost-effective catalyst in heterogeneous Fenton-like systems for mineralization and degradation of emerging contaminants such as antibiotics.

研究了一种以非均相的Fenton状黄铁矿/ H ₂ O ₂为原料，以矿山废料中的黄铁矿为原料降解四环素的方法。该研究的重点是确定主要的氧化剂和降解机理，以及包括溶液pH值，黄铁矿和H ₂ O ₂浓度，接触时间，溶液温度和初始TTC浓度在内的操作变量。催化剂表征测试表明，黄铁矿是具有高FeS ₂纯度的中孔粉末。自由基清除剂测试表明^• OH是溶液和表面相反应所产生的主要氧化剂。黄铁矿/ H ₂ O_2个过程中，在60分钟内矿化了超过85％的TTC，并且在酸性pH值（4.1）下溶液中的TTC去除量达到了最大值。通过^• OH自由基的攻击形成的TTC最丰富的转化产物是单链羧酸。人类胚胎肾脏（HEK）培养的细胞用于评估生铁矿和黄铁矿/ H ₂ O ₂的细胞毒性处理过的TTC解决方案。结果表明，在最佳条件下处理TTC溶液后，HEK细胞的活力大大提高。因此，源自矿山废物的黄铁矿在非均质的Fenton样系统中是一种实用有效且具有成本效益的催化剂，用于矿化和降解新兴污染物（如抗生素）。