Abstract

The reaction of 2-imino-2,5-dihydrofuran-3-carboxamides with benzaldehyde in pentan-1-ol in the presence of piperidine gave new dihydrofuran derivatives with a fused pyrimidine ring and two phenyl rings, 2-phenyl-5-(2-phenylethylidene)-5,6-dihydrofuro[2,3-d]pyrimidin-4(3H)-ones. The product structure was confirmed by spectroscopic methods (¹H and ¹³C NMR) and independent synthesis from previously reported 2-imino-5,5-dimethyl-4-(2-phenylethenyl)-2,5-dihydrofuran-3-carboxamide and benzaldehyde under similar conditions.

中文翻译：

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2-Imino-2,5-二氢呋喃-3-羧酰胺与苯甲醛的反应

摘要

2-亚氨基-2,5-二氢呋喃-3-羧酰胺与戊醛在戊烷中的戊醛在哌啶存在下的反应生成了具有稠合嘧啶环和两个苯环的新二氢呋喃衍生物，2-苯基-5-（ 2-苯基亚乙基）-5，6-二氢呋喃并[2，3- d ]嘧啶-4（3 H）-ones。通过光谱方法（¹ H和¹³ C NMR）以及由先前报道的2-亚氨基-5,5-二甲基-4-（2-苯基乙烯基）-2,5-二氢呋喃-3-羧酰胺和在类似条件下的苯甲醛。