This study aimed to estimate genetic parameters for four guinea pig lines of a crossbreeding scheme. Two paternal lines are selected for growth rate (P1) and feed conversion rate (P2), whereas two maternal lines are selected for growth rate of litter (M1) and litter size at birth (M2). The heritabilities and genetic correlations were estimated with animal linear models employing multivariate analyses with REML. The heritabilities for birth weight (BW) were 0.21±0.02 and 0.23±0.03 for P1 and P2, respectively, and for weaning weight (WW), the heritability was 0.28±0.03 for P2. The estimates for weight at 60 days of age (W60) were 0.34±0.01 and 0.47±0.04 for P1 and P2, respectively, and for partial feed conversion rate was 0.46±0.03 for P2. Heritabilities for litter weight at birth (LW) were 0.09±0.03 and 0.10±0.03 for P1 and M1, respectively. For litter weight at 10 days of age (LW10), the heritability was 0.15±0.03 for M1. Heritabilities for litter size (LS) were 0.17±0.03, 0.20±0.03 and 0.11±0.03, and for number of pups born alive (BA) were 0.09±0.03, 0.14±0.03 and 0.09±0.03 for P1, M1 and M2, respectively. Similarly, high genetic correlations were found between BW, WW and W60 and between LW, LS, LW10 and BA. The genetic correlation between BW direct and maternal was moderately negative (− 0.24 ± 0.10) for P1. These results show the genetic status for all four guinea pig lines, which is essential for the further improvement of the currently implemented breeding programme and also indicate an opportunity for genetic improvement.

这项研究旨在估计杂交方案的四个豚鼠品系的遗传参数。选择两个父系作为生长率（P1）和饲料转化率（P2），而两个母系则选择为产仔率（M1）和出生时产仔数（M2）。遗传力和遗传相关性是通过动物线性模型使用REML进行多变量分析来估计的。P1和P2的出生体重（BW）遗传力分别为0.21±0.02和0.23±0.03，而断奶重（WW）的遗传力对于P2为0.28±0.03。P1和P2在60日龄时的体重估计值（W60）分别为0.34±0.01和0.47±0.04，P2的部分饲料转化率为0.46±0.03。P1和M1的出生时产仔体重（LW）的遗传力分别为0.09±0.03和0.10±0.03。对于10天龄（LW10）的猫砂重量，M1的遗传力为0.15±0.03。P1，M1和M2的产仔数（LS）遗传力分别为0.17±0.03、0.20±0.03和0.11±0.03，活产幼崽数（BA）分别为0.09±0.03、0.14±0.03和0.09±0.03 。同样，在BW，WW和W60之间以及LW，LS，LW10和BA之间发现高度的遗传相关性。体重直接与母体之间的遗传相关性对P1呈中等负值（-0.24±0.10）。这些结果显示了所有四个豚鼠品系的遗传状况，这对于进一步改善当前实施的育种计划至关重要，也表明了遗传改良的机会。P1，M1和M2的幼崽存活率（BA）分别为0.09±0.03、0.14±0.03和0.09±0.03。同样，在BW，WW和W60之间以及LW，LS，LW10和BA之间发现了高度的遗传相关性。体重直接与母体之间的遗传相关性对P1呈中等负值（-0.24±0.10）。这些结果显示了所有四个豚鼠品系的遗传状况，这对于进一步改善当前实施的育种计划至关重要，也表明了遗传改良的机会。P1，M1和M2的幼崽存活率（BA）分别为0.09±0.03、0.14±0.03和0.09±0.03。同样，在BW，WW和W60之间以及LW，LS，LW10和BA之间发现了高度的遗传相关性。体重直接与母体之间的遗传相关性对P1呈中等负值（-0.24±0.10）。这些结果显示了所有四个豚鼠品系的遗传状况，这对于进一步改善当前实施的育种计划至关重要，也表明了遗传改良的机会。