The human population growth has been followed by an infection rate increase of pathogenic bacteria. The continual use of synthetic antibacterial chemicals has negative effects, pathogenic bacterial resistance of high doses. Therefore, the discovery of a new antibacterial agent is an urgent need. The search for new drug agents as antibacteria has expanded to marine organisms, especially seaweeds. This research aimed to measure the clear zone of seaweeds against bacterial tests and to evaluate the ability of seaweed as an antibacterial agent. The seaweed samples were collected from Pantai Panjang, Bengkulu, Indonesia, using a purposive sampling method. Maceration method used to extract the antibacterial agent from seaweeds. Agar diffusion method was used as an antibacterial activity assay against Escherichia coli, Salmonella typhii, and Staphylococcus aureus as the tested bacteria. There were three species of seaweeds found in the location e.g., Halimeda discoidea, Halimeda micronesica, and Caulerpa taxifolia. The antibacterial assay indicated that H. discoidea and C. taxifolia have the antibacterial activity against all tested bacteria with a clear zone that categorized into moderate and high. Meanwhile, H. micronesica had the potential as an antibacterial agent against E. coli and S. typhii with a clear zone categorized into moderate and high. In the future, it could be a potential new drug agent, especially for an antibacterial agent.

随着人口的增长，病原菌的感染率也随之增加。持续使用合成抗菌化学品有负面影响，高剂量的病原菌耐药。因此，迫切需要发现一种新的抗菌剂。寻找新的抗菌药物制剂已扩展到海洋生物，尤其是海藻。本研究旨在通过细菌测试测量海藻的透明区域，并评估海藻作为抗菌剂的能力。使用有目的的采样方法从印度尼西亚明古鲁的 Pantai Panjang 收集海藻样品。用于从海藻中提取抗菌剂的浸渍法。琼脂扩散法作为抗菌活性测定法大肠杆菌、伤寒沙门氏菌和金黄色葡萄球菌作为测试细菌。在该地点发现了三种海藻，例如Halimeda discoidea、Halimeda micronesica和Caulerpa taxfolia。抑菌试验表明，盘蚴和松叶杉对所有受试细菌均具有抑菌活性，具有明显的中度和高度区。同时，密克罗尼西亚嗜血杆菌具有作为抗大肠杆菌和伤寒沙门氏菌的抗菌剂的潜力有一个清晰的区域，分为中等和高。未来，它可能是一种潜在的新药物，尤其是抗菌剂。