Abstract

A new homo-aro-cholestane glycoside parispolyside H, along with nine known compounds, were isolated from 75% ethanolic extract of the rhizome of Paris polyphylla var. chinensis. Their chemical structures were elucidated on the basic of analysis of detailed spectroscopic and physicochemical properties. In addition, the isolated compounds (1, 6-9) were evaluated for their cytotoxic activity against HepG2 human liver cancer cell lines. Among them, four known compounds (6-9) showed cytotoxicity with IC₅₀ values ranging from 0.41 to 3.6 μM.

中文翻译：

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一种来自Paris polyphylla var的根茎的新的高-芳香-胆甾烷糖苷。中华

摘要

从巴黎多叶植物的根茎的75％乙醇提取物中分离出一种新的高-芳香族-胆甾烷糖苷parispolyside H，以及九种已知化合物。中华。在详细分析光谱和理化性质的基础上阐明了它们的化学结构。此外，分离的化合物（1，6 - 9）它们对HepG2人肝癌细胞系的细胞毒活性进行评价。其中，四个已知化合物（6 - 9）显示出细胞毒性，IC _50个值范围为0.41至3.6微米。