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Mechanistic insights into Candida biofilm eradication potential of eucalyptol
Journal of Applied Microbiology ( IF 4 ) Pub Date : 2020-11-23 , DOI: 10.1111/jam.14940
P Gupta 1 , V Pruthi 1 , K M Poluri 1, 2
Affiliation  

Candida-associated fungal infections are prevalent in hospitalized and immune-compromised patients. Their biofilm architecture and high rate of antifungal resistance make treatment challenging. Eucalyptol (EPTL), a monoterpene majorly present in the essential oil of eucalyptus is well known for curing respiratory infections. Hence, the present study investigated the anti-biofilm efficacy of EPTL against the laboratory strains and clinical isolates of Candida to delineate its mode of action.

中文翻译:

桉树脑对念珠菌生物膜根除潜力的机理研究

念珠菌相关的真菌感染在住院和免疫功能低下的患者中很普遍。它们的生物膜结构和高抗真菌耐药率使治疗具有挑战性。桉树油 (EPTL) 是一种主要存在于桉树精油中的单萜,以治疗呼吸道感染而闻名。因此,本研究调查了 EPTL 对实验室菌株和念珠菌临床分离株的抗生物膜功效,以描述其作用模式。
更新日期:2020-11-23
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