Metabolic syndrome (MetS) and obesity are growing in many parts of the world, becoming public health problems. It is proposed that foods with functional properties can assist in the treatment of these diseases. Crude buriti pulp oil (BPO) is a food traditionally consumed by residents in the Pantanal, Cerrado and Brazilian Amazon. It is rich in oleic acid, tocopherols and carotenoids, emerging as a potential functional food. Thus, this study aimed to evaluate the effect of the supplementation of BPO on metabolic disorders caused by a high‐fat diet. Four groups of C57BL6 mice were used, a lean group with AIN‐93M diet and control oil supplementation, an obese group with a high‐fat diet and control oil supplementation, and two obese groups with a high‐fat diet and BPO supplementation in the amounts of 50 and 100 mg/kg. BPO worsened the metabolic state caused by the high‐fat diet, worsening risk factors associated with MetS, as the abdominal circumference and retroperitoneal fat, serum levels of total cholesterol, uric acid, alanine transaminase, glucose and triglycerides, and renal fat, in addition to changes in glycaemic control and oxidative stress markers. C57BL/6 mice fed with a high‐fat diet and supplemented with BPO presented a worsening in metabolic risk factors associated with MetS.

中文翻译：

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Buriti 果肉油不能改善 c57bl/6 小鼠高脂饮食引起的代谢紊乱

代谢综合征 (MetS) 和肥胖症在世界许多地方都在增加，成为公共卫生问题。建议具有功能特性的食物可以帮助治疗这些疾病。原浆油 (BPO) 是潘塔纳尔湿地、塞拉多和巴西亚马逊地区居民传统上食用的一种食物。它富含油酸、生育酚和类胡萝卜素，是一种潜在的功能性食品。因此，本研究旨在评估补充 BPO 对高脂饮食引起的代谢紊乱的影响。使用四组 C57BL6 小鼠，AIN-93M 饮食和控制油补充的瘦组，高脂饮食和控制油补充的肥胖组，以及高脂肪饮食和 BPO 补充的两个肥胖组。 50 和 100 毫克/公斤的量。BPO 使高脂肪饮食引起的代谢状态恶化，使与 MetS 相关的危险因素恶化，如腹围和腹膜后脂肪、血清总胆固醇水平、尿酸、丙氨酸转氨酶、葡萄糖和甘油三酯以及肾脂肪，此外血糖控制和氧化应激标志物的变化。以高脂肪饮食喂养并补充 BPO 的 C57BL/6 小鼠表现出与 MetS 相关的代谢风险因素恶化。