A Wearable Nutrition Tracker,Advanced Materials

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A Wearable Nutrition Tracker
Advanced Materials ( IF 27.4 ) Pub Date : 2020-11-23 , DOI: 10.1002/adma.202006444
Jiangqi Zhao _{1,

2,

3} , Hnin Yin Yin Nyein _{1,

2,

3} , Lei Hou _{1,

3} , Yuanjing Lin _{1,

2,

3,

4} , Mallika Bariya _{1,

2,

3} , Christine Heera Ahn ₁ , Wenbo Ji _{1,

2,

3} , Zhiyong Fan ₄ , Ali Javey _{1,

2,

3}

Affiliation

Nutrients are essential for the healthy development and proper maintenance of body functions in humans. For adequate nourishment, it is important to keep track of nutrients level in the body, apart from consuming sufficient nutrition that is in line with dietary guidelines. Sweat, which contains rich chemical information, is an attractive biofluid for routine non‐invasive assessment of nutrient levels. Herein, a wearable sensor that can selectively measure vitamin C concentration in biofluids, including sweat, urine, and blood is developed. Detection through an electrochemical sensor modified with Au nanostructures, LiClO₄‐doped conductive polymer, and an enzymes‐immobilized membrane is utilized to achieve wide detection linearity, high selectivity, and long‐term stability. The sensor allows monitoring of temporal changes in vitamin C levels. The effect of vitamin C intake on the sweat and urine profile is explored by monitoring concentration changes upon consuming different amounts of vitamin C. A longitudinal study of sweat's and urine's vitamin C correlation with blood is performed on two individuals. The results suggest that sweat and urine analysis can be a promising method to routinely monitor nutrition through the sweat sensor and that this sensor can facilitate applications such as nutritional screening and dietary intervention.

中文翻译：

可穿戴营养追踪器

营养素对于人类的健康发育和身体功能的适当维持至关重要。为了获得充足的营养，除了按照饮食指南摄入足够的营养外，跟踪体内的营养水平也很重要。汗液含有丰富的化学信息，对于营养水平的常规非侵入性评估来说是一种有吸引力的生物流体。在此，开发了一种可穿戴传感器，可以选择性地测量生物体液（包括汗液、尿液和血液）中的维生素 C 浓度。利用金纳米结构、LiClO ₄掺杂导电聚合物和酶固定膜修饰的电化学传感器进行检测，可实现宽检测线性、高选择性和长期稳定性。该传感器可以监测维生素 C 水平的时间变化。通过监测摄入不同量维生素 C 时的浓度变化，探讨维生素 C 摄入量对汗液和尿液的影响。对两个人进行了汗液和尿液中维生素 C 与血液相关性的纵向研究。结果表明，汗液和尿液分析可能是通过汗液传感器常规监测营养的一种有前途的方法，并且该传感器可以促进营养筛查和饮食干预等应用。

更新日期：2021-01-04

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