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Noncoding RNA, Intragenomic Conflict, and Rodent SRY Evolution
Trends in Genetics ( IF 13.6 ) Pub Date : 2020-11-23 , DOI: 10.1016/j.tig.2020.11.004
Scott William Roy 1
Affiliation  

The sex-determining gene SRY has undergone rapid evolution in rodents. Curiously, a new study by Miyawaki et al. reveals that a recently evolved SRY gene sequence antagonizes SRY protein stability, necessitating splicing of a novel intron. Other data suggest that this troublesome gene region has noncoding RNA functions, possibly related to conflict between sex chromosomes.



中文翻译:

非编码RNA,Intragenomic冲突和啮齿动物SRY进化

性别决定基因SRY在啮齿动物中经历了快速进化。奇怪的是,宫胁等人的一项新研究揭示了最近进化的SRY基因序列拮抗SRY蛋白质的稳定性,因此需要剪接新的内含子。其他数据表明,这个麻烦的基因区域具有非编码RNA功能,可能与性染色体之间的冲突有关。

更新日期:2021-01-19
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