Phthalate plasticizers (PAEs) are heavily applied to plastic products and poses severe threat to human health. Herein, it is especially urgent to find a stable and reliable method for detecting PAEs. In this report, a Surface Enhanced Raman Scatting (SERS) strategy coupled with plasmonic core–shell Au nanospheres@Ag nanocubes (AuNS@AgNCs) as substrates were employed for the rapid and sensitive detection of Butyl benzyl phthalate (BBP) in liquor samples, and plasmonic core–shell AuNS@AgNCs tend to perform richer localized surface plasmon resonance (LSPR) than AuNS. In this work, different sizes AuNS@AgNCs comprised of Au nanospheres as core and Ag nanocubes as shells were synthesized. Based on this, we then investigated the SERS activity of BBP and crystal violet (CV) reached a maximum level when the thickness of Ag coating shell arrived in a threshold, and even very low signal of trace BBP dissolved in liquor sample can be detected in existence of the plasmonic AuNS@AgNCs active substrate of 50 nm. The sensitivity and repeatability of the optimized size AuNs@AgNCs have been estimated and limits of detection (LOD) was 10^-9 M for BBP. In addition, finite difference time domain (FDTD) electromagnetic simulations also performed in great agreement with our experimental results.

邻苯二甲酸酯增塑剂（PAE）大量应用于塑料产品，对人体健康构成严重威胁。在此，迫切需要找到一种稳定可靠的检测PAE的方法。在本报告中，采用表面增强拉曼散射（SERS）策略与等离激元核-壳金纳米球@Ag纳米立方体（AuNS @ AgNCs）作为底物，用于快速，灵敏地检测液体样品中的邻苯二甲酸丁苄酯（BBP），等离子体核-壳AuNS @ AgNCs倾向于比AuNS进行更丰富的局部表面等离子体共振（LSPR）。在这项工作中，合成了不同大小的AuNS @ AgNCs，它们以Au纳米球为核，Ag纳米立方体为壳。基于此，然后，我们研究了当银涂层外壳的厚度达到阈值时，BBP的SERS活性和结晶紫（CV）达到最大水平，甚至在血浆中也可以检测到溶解于液体样品中的痕量BBP的信号非常低。 50 nm的AuNS @ AgNCs活性底物。已估算了优化尺寸的AuNs @ AgNC的灵敏度和可重复性，检出限（LOD）为10^-9 M代表BBP。此外，有限差分时域（FDTD）电磁仿真也与我们的实验结果非常吻合。