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Cooperative enhancement of fungal repelling performance by surface photografting of stereochemical bi-molecules
Colloid and Interface Science Communications ( IF 4.7 ) Pub Date : 2020-11-23 , DOI: 10.1016/j.colcom.2020.100336
Chen Chen , Zixu Xie , Pengfei Zhang , Yanhui Liu , Xing Wang

Fungal contamination could increase exponentially on any convenient sites if without antifungal agents, thus seriously threatening human health. In this work, a cooperative fungal repelling coating has been fabricated by surface photografting polymerization of bi-molecules, polyethylene glycol diacrylate (PEGDA) and bornyl acrylate (BA), which combined amphiphilic feature with stereochemical fungal repelling strategy. ATR-FTIR and EDS were used to confirm the synthesized copolymers. The surface microstructures of the coating film were showed with AFM and SEM images. The cooperative enhancement of fungal repelling performance has been demonstrated through modulating the ratio between hydrophilic PEGDA and hydrophobic BA. When the ratio of monomers was 1:1, the coating exhibited the best cooperative effect on anti-adhesion of Aspergillus niger. Binary cooperation between PEG ring and bornyl cage is considered to play a crucial role in this coating system. Therefore, amphiphilic-stereochemistry is believed to be an effective strategy to prevent fungal adhesion.



中文翻译:

通过表面化学嫁接的立体化学双分子协同增强真菌的排斥性能

如果没有抗真菌剂,真菌的污染在任何方便的地方都可能成倍增加,从而严重威胁人类健康。在这项工作中,通过将两亲性特征与立体化学真菌排斥策略相结合的双分子,聚乙二醇二丙烯酸酯(PEGDA)和丙烯酸冰片酯(BA)的表面光接枝聚合反应,制备了协同的真菌排斥涂层。使用ATR-FTIR和EDS确认合成的共聚物。用AFM和SEM图像显示涂膜的表面微观结构。通过调节亲水性PEGDA和疏水性BA之间的比例,证明了真菌排斥性能的协同增强。当单体比例为1:1时,涂层对防粘连性表现出最好的协同作用。黑曲霉。PEG环和冰片笼之间的二元合作被认为在该包衣系统中起关键作用。因此,两亲性立体化学被认为是防止真菌粘附的有效策略。

更新日期:2020-11-23
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