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Potential impact of biocide adaptation on selection of antibiotic resistance in bacterial isolates
Future Journal of Pharmaceutical Sciences ( IF 3.4 ) Pub Date : 2020-11-21 , DOI: 10.1186/s43094-020-00119-w
Engy Elekhnawy , Fatma Sonbol , Ahmed Abdelaziz , Tarek Elbanna

Antibiotic resistance in pathogenic bacterial isolates has increased worldwide leading to treatment failures. Many concerns are being raised about the usage of biocidal products (including disinfectants, antiseptics, and preservatives) as a vital factor that contributes to the risk of development of antimicrobial resistance which has many environmental and economic impacts. Consequently, it is important to recognize the different types of currently used biocides, their mechanisms of action, and their potential impact to develop cross-resistance and co-resistance to various antibiotics. The use of biocides in medical or industrial purposes should be monitored and regulated. In addition, new agents with biocidal activity should be investigated from new sources like phytochemicals in order to decrease the emergence of resistance among bacterial isolates.

中文翻译:

杀菌剂适应性对细菌分离物中抗生素抗性选择的潜在影响

致病性细菌分离物中的抗生素抗性在全世界范围内增加,导致治疗失败。人们对使用杀生物产品(包括消毒剂,防腐剂和防腐剂)作为至关重要的因素提出了很多担忧,这些因素是导致产生耐药性风险的重要因素,这会对环境和经济产生许多影响。因此,重要的是要认识到当前使用的不同类型的杀菌剂,它们的作用机理以及它们对各种抗生素产生交叉耐药性和共同耐药性的潜在影响。应监控和规范在医疗或工业用途中使用杀生物剂。此外,
更新日期:2020-11-22
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