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Manual Acupuncture or Combination with Vitamin B to Treat Diabetic Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
BioMed Research International ( IF 2.6 ) Pub Date : 2020-11-21 , DOI: 10.1155/2020/4809125
Hai Lun Jiang 1, 2, 3 , Peng Jia 4 , Yi Hua Fan 1, 2, 3 , Meng Dan Li 1, 2, 3 , Can Can Cao 1, 2, 3 , Yuan Li 2 , Yu Zheng Du 1, 3
Affiliation  

Background and Objective. The efficacy of mecobalamin (vitamin B12) alone in the treatment of diabetic peripheral neuropathy (DPN) is often unsatisfactory, while acupuncture treatment is also controversial. This study compares manual acupuncture to vitamin B in DPN treatment. Methods. Randomized controlled trials on manual acupuncture treatment of DPN were retrieved from the Medline, Web of Science, PubMed, Cochrane Library, EMBASE, CNKI, WanFang, and VIP databases. Extracted research data were summarized in the tables, and methodological assessment was performed using the risk-of-bias assessment tool of Cochrane. Meta-analysis was performed by Revman 5.3, Stata 14.0, and TSA 0.9.5.10 Beta software. Results. A total of 18 randomized clinical trials (RCTs) were recruited: (1) 11 RCTs were acupuncture alone compared with vitamin B; (2) 7 RCTs were acupuncture combined with vitamin B compared with vitamin B, involving 1200 participants. Acupuncture alone improved clinical efficacy () and nerve conduction velocity of the four peripheral nerves: peroneal nerve, tibial nerve, median nerve, and ulnar nerve (), but there was no significant difference between the group of acupuncture alone and the group of vitamin B () in improving median nerve SCV (sensory nerve conduction velocity). Acupuncture combined with vitamin B improved clinical efficacy and nerve conduction velocity of the three peripheral nerves, peroneal nerve, tibial nerve, and median nerve (), and decreased the scores of the Toronto clinical scoring system (TCSS) (). Conclusion. Acupuncture alone and vitamin B combined with acupuncture are more effective in treating DPN compared to vitamin B. However, more high-quality RCTs on vitamin B combined with acupuncture are required to confirm our results.

中文翻译:


手法针灸或联合维生素 B 治疗糖尿病周围神经病变:随机对照试验的系统回顾和荟萃分析



背景和目的。单独应用甲钴胺(维生素B 12 )治疗糖尿病周围神经病变(DPN)的疗效往往不理想,而针灸治疗也存在争议。本研究比较了 DPN 治疗中的手工针灸与维生素 B 的效果。方法。从 Medline、Web of Science、PubMed、Cochrane Library、EMBASE、CNKI、WanFang 和 VIP 数据库检索手法针刺治疗 DPN 的随机对照试验。提取的研究数据总结在表格中,并使用 Cochrane 的偏倚风险评估工具进行方法学评估。采用 Revman 5.3、Stata 14.0 和 TSA 0.9.5.10 Beta 软件进行荟萃分析。结果。共招募18项随机临床试验(RCT):(1)11项RCT为单独针灸与维生素B的比较; (2)针刺联合维生素B与维生素B进行比较的随机对照试验7项,涉及1200名受试者。 单独针灸可提高临床疗效( 和四种周围神经:腓神经、胫神经、正中神经和尺神经的神经传导速度( ),但单独针刺组和维生素 B 组之间没有显着差异( 改善正中神经SCV(感觉神经传导速度)。 针刺结合维生素B可提高临床疗效,提高腓神经、胫神经、正中神经三种周围神经的神经传导速度。 ),并降低了多伦多临床评分系统(TCSS)的分数( )。结论。与维生素 B 相比,单独针灸和维生素 B 联合针灸治疗 DPN 更有效。然而,需要更多关于维生素 B 联合针灸的高质量随机对照试验来证实我们的结果。
更新日期:2020-11-22
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