Adropin is a nutritionally regulated peptide hormone, secreted primarily by the liver, which modulates metabolic homeostasis in a number of tissues. Growing evidence suggests that adropin is an important regulatory component in a number of cardiovascular pathologies, and may be central to the control of cardiac fuel metabolism and vascular function. In this mini-review, we examine the known facets of adropin biology, discuss open questions in the field, and speculate on the therapeutic potential of targeting adropin-related signaling pathways in cardiovascular diseases.

中文翻译：

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ADROPIN：血管功能和心脏燃料代谢的肝素调节剂

Adropin 是一种营养调节肽激素，主要由肝脏分泌，可调节许多组织的代谢稳态。越来越多的证据表明，adropin 是许多心血管疾病的重要调节成分，并且可能是控制心脏燃料代谢和血管功能的核心。在这篇小型综述中，我们研究了 adropin 生物学的已知方面，讨论了该领域的开放性问题，并推测了靶向 adropin 相关信号通路在心血管疾病中的治疗潜力。