The commissioning and benchmark of a Monte Carlo (MC) model of the 6‐MV Brainlab‐Mitsubishi Vero4DRT linear accelerator for the purpose of quality assurance of clinical dynamic wave arc (DWA) treatment plans is reported. Open‐source MC applications based on EGSnrc particle transport codes are used to simulate the medical linear accelerator head components. Complex radiotherapy irradiations can be simulated in a single MC run using a shared library format combined with BEAMnrc “source20.” Electron energy tuning is achieved by comparing measured vs simulated percentage depth doses (PDDs) for MLC‐defined field sizes in a water phantom. Electron spot size tuning is achieved by comparing measured and simulated inplane and crossplane beam profiles. DWA treatment plans generated from RayStation (RaySearch) treatment planning system (TPS) are simulated on voxelized (2.5 mm³) patient CT datasets. Planning target volume (PTV) and organs at risk (OAR) dose–volume histograms (DVHs) are compared to TPS‐calculated doses for clinically deliverable dynamic volumetric modulated arc therapy (VMAT) trajectories. MC simulations with an electron beam energy of 5.9 MeV and spot size FWHM of 1.9 mm had the closest agreement with measurement. DWA beam deliveries simulated on patient CT datasets results in DVH agreement with TPS‐calculated doses. PTV coverage agreed within 0.1% and OAR max doses (to 0.035 cc volume) agreed within 1 Gy. This MC model can be used as an independent dose calculation from the TPS and as a quality assurance tool for complex, dynamic radiotherapy treatment deliveries. Full patient CT treatment simulations are performed in a single Monte Carlo run in 23 min. Simulations are run in parallel using the Condor High‐Throughput Computing software¹ on a cluster of eight servers. Each server has two physical processors (Intel Xeon CPU E5‐2650 0 @2.00 GHz), with 8 cores per CPU and two threads per core for 256 calculation nodes.

中文翻译：

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使用EGSnrc移动源的Vero4DRT线性加速器对6-MV动态波VMAT交付的蒙特卡罗模拟

为了保证临床动态波弧（DWA）治疗计划的质量，报告了6-MV Brainlab-Mitsubishi Vero4DRT线性加速器的Monte Carlo（MC）模型的调试和基准测试。基于EGSnrc粒子传输代码的开源MC应用程序用于模拟医用线性加速器头部组件。可以使用共享库格式结合BEAMnrc“ source20”在单个MC运行中模拟复杂的放射疗法照射。通过比较水模型中MLC定义的场大小，可以通过比较实测的百分比剂量和模拟的深度百分比剂量（PDD）来实现电子能量的调整。通过比较测得的和模拟的面内和交叉面光束轮廓来实现电子光斑尺寸的调整。³）患者CT数据集。将计划目标体积（PTV）和高危器官（OAR）剂量-体积直方图（DVHs）与TPS计算的剂量进行比较，以得出可临床交付的动态容积调制弧光治疗（VMAT）轨迹。电子束能量为5.9 MeV且光斑尺寸FWHM为1.9 mm的MC模拟与测量值最接近。在患者CT数据集上模拟的DWA光束传输结果使DVH与TPS计算的剂量一致。PTV覆盖范围在0.1％以内，OAR最大剂量（达到0.035 cc体积）在1 Gy范围内。该MC模型可以用作TPS的独立剂量计算，也可以用作复杂，动态放射疗法治疗交付的质量保证工具。在23分钟的单次Monte Carlo运行中执行完整的患者CT治疗模拟。在八个服务器的群集上为¹。每个服务器都有两个物理处理器（Intel Xeon CPU E5-2650 0 @ 2.00 GHz），每个CPU具有8个内核，每个内核具有两个线程，可用于256个计算节点。