• The controlled release of IL-4 and dexamethasone by a dual-wavelength photosensitive nano-in-micro scaffold (biphasic calcium phosphate loaded with goad nanocage, BCP-GNC) enables the regulation of specific immune cells and immune responses.

• BCP-GNC regulates innate and adaptive immune responses in two stages (directing the M2 polarization of macrophages and inhibiting the maturation of dendritic cells) to promote osteoinduction.

中文翻译：

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双波长光敏纳米-微型支架调节成骨的先天和适应性免疫反应

• 通过双波长光敏纳米微支架（装载有刺针纳米笼的双相磷酸钙，BCP-GNC）控制释放 IL-4 和地塞米松，可以调节特定的免疫细胞和免疫反应。

• BCP-GNC 在两个阶段（指导巨噬细胞的 M2 极化和抑制树突状细胞的成熟）调节先天性和适应性免疫反应，以促进骨诱导。