Tissue engineering which is applied in regenerative medicine has three basic components: cells, scaffolds and growth factors. This multidisciplinary field can regulate cell behaviors in different conditions using scaffolds and growth factors. Scaffolds perform this regulation with their structural, mechanical, functional and bioinductive properties and growth factors by attaching to and activating their receptors in cells. There are various types of biological extracellular matrix (ECM) and polymeric scaffolds in tissue engineering. Recently, many researchers have turned to using biological ECM rather than polymeric scaffolds because of its safety and growth factors. Therefore, selection the right scaffold with the best properties tailored to clinical use is an ideal way to regulate cell behaviors in order to repair or improve damaged tissue functions in regenerative medicine. In this review we first divided properties of biological scaffold into intrinsic and extrinsic elements and then explain the components of each element. Finally, the types of scaffold storage methods and their advantages and disadvantages are examined.

应用于再生医学的组织工程具有三个基本组成部分：细胞、支架和生长因子。这个多学科领域可以使用支架和生长因子在不同条件下调节细胞行为。支架通过附着并激活细胞中的受体，利用其结构、机械、功能和生物诱导特性以及生长因子来执行这种调节。组织工程中有多种类型的生物细胞外基质 (ECM) 和聚合物支架。最近，由于其安全性和生长因子，许多研究人员已转向使用生物 ECM 而不是聚合物支架。所以，选择适合临床使用的具有最佳特性的正确支架是调节细胞行为以修复或改善再生医学中受损组织功能的理想方法。在这篇综述中，我们首先将生物支架的特性分为内在和外在要素，然后解释了每个要素的组成部分。最后，检查了支架存储方法的类型及其优缺点。