FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules,Nanoscale

当前位置： X-MOL 学术 › Nanoscale › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules
Nanoscale ( IF 5.8 ) Pub Date : 2020-11-13 , DOI: 10.1039/d0nr05800a
Yehlin Cho _{1,

2,

3,

4} , Junyoung Seo _{1,

2,

3,

4} , Yeonbo Sim _{5,

6,

7,

8} , Jinkyoung Chung _{4,

9,

10,

11} , Chan E. Park _{1,

2,

3,

4} , Chun Gwon Park _{5,

6,

7,

8,

12} , Doory Kim _{4,

9,

10,

11} , Jae-Byum Chang _{1,

2,

3,

4,

13}

Affiliation

In this article, we demonstrate fluorescent signal amplification via cyclic staining of target molecules (FRACTAL), a technique that can amplify the signal intensity of immunofluorescence staining more than nine-fold via simple cyclic staining of secondary antibodies. We also show that FRACTAL is compatible with four-color imaging and expansion microscopy imaging.

中文翻译：