The topographic organization of afferents to the hippocampal CA3 subfield are well-studied, but their role in influencing the spatiotemporal dynamics of population activity is not understood. Using a large-scale, computational neuronal network model of the entorhinal-dentate-CA3 system, the effects of the perforant path, mossy fibers, and associational system on the propagation and transformation of network spiking patterns were investigated. A correlation map was constructed to characterize the spatial structure and temporal evolution of pairwise correlations which underlie the emergent patterns found in the population activity. The topographic organization of the associational system gave rise to changes in the spatial correlation structure along the longitudinal and transverse axes of the CA3. The resulting gradients may provide a basis for the known functional organization observed in hippocampus.

中文翻译：

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由于兴奋性传入，大鼠海马 CA3 纵轴和横轴相关性的地形组织

海马 CA3 亚区传入神经的地形组织已得到充分研究，但它们在影响种群活动时空动态方面的作用尚不清楚。使用内嗅-齿状-CA3 系统的大规模计算神经元网络模型，研究了穿孔路径、苔藓纤维和关联系统对网络尖峰模式的传播和转换的影响。构建了相关图来表征成对相关性的空间结构和时间演变，这些相关性是种群活动中发现的新兴模式的基础。关联系统的地形组织引起了沿 CA3 纵轴和横轴的空间关联结构的变化。