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Highly Versatile Cloud-Based Automation Solution for the Remote Design and Execution of Experiment Protocols during the COVID-19 Pandemic
SLAS Technology: Translating Life Sciences Innovation ( IF 2.5 ) Pub Date : 2020-11-19 , DOI: 10.1177/2472630320971218
Piero Zucchelli 1 , Giorgio Horak 1 , Nigel Skinner 1
Affiliation  

There is an urgent need to accelerate the development and validation of both diagnostics and vaccines for COVID-19. These priorities are challenging both public and private sector research groups around the world and have shone a spotlight on both existing bottlenecks in the research workflows involved as well as on the implications of having to do much of this work remotely because of enforced social distancing and lockdown measures. The ability to respond quickly to rapidly evolving events, coupled with an emerging understanding of the disease and its pathology, as well as different mutations of the virus, necessitates a highly flexible liquid-handling automation solution that is amenable to rapid switching between different assay workflows and processes to be exploited tactically as needed. In addition, the use of cloud-based software imparts a unique benefit in enabling multiple research groups and remote technical staff around the world to have ready access to the same protocols in real-time without delays, down to the required level of detail, sharing methods and data (for example, in faster clinical trials). Informed by a recent use case, this article explores these issues alongside the recent development and deployment of an automation solution, whose unique approach in terms of both its cloud-native software and its highly modular hardware aligns especially well with achieving the challenge set by this new frontier in the bioanalytical laboratory.



中文翻译:

高度通用的基于云的自动化解决方案,可在COVID-19大流行期间远程设计和执行实验协议

迫切需要加快对COVID-19的诊断和疫苗的开发和验证。这些优先事项正挑战着世界各地的公共和私营部门研究小组,并且聚焦于所涉及的研究工作流程中的现有瓶颈,以及由于强制性的社会疏远和封锁而不得不远程进行大量此类工作的影响措施。快速响应快速发展的事件的能力,以及对疾病及其病理学以及病毒不同突变的新认识,需要高度灵活的液体处理自动化解决方案,该解决方案必须能够在不同的检测工作流程之间快速切换以及根据需要在战术上加以利用的流程。此外,使用基于云的软件具有独特的优势,它使世界各地的多个研究小组和远程技术人员能够实时,实时地访问同一协议,而不会出现延迟,直至达到所需的详细程度,共享方法和数据(例如,在更快的临床试验中)。鉴于最近的一个使用案例,本文探索了这些问题以及自动化解决方案的最新开发和部署,该解决方案在其云原生软件和高度模块化的硬件方面的独特方法尤其适合于解决这一挑战。生物分析实验室的新领域。达到所需的详细程度,共享方法和数据(例如,在更快的临床试验中)。鉴于最近的一个使用案例,本文探索了这些问题以及自动化解决方案的最新开发和部署,该解决方案在其云原生软件和高度模块化的硬件方面的独特方法尤其适合于解决这一挑战。生物分析实验室的新领域。达到所需的详细程度,共享方法和数据(例如,在更快的临床试验中)。鉴于最近的一个使用案例,本文探索了这些问题以及自动化解决方案的最新开发和部署,该解决方案在其云原生软件和高度模块化的硬件方面的独特方法尤其适合于解决这一挑战。生物分析实验室的新领域。

更新日期:2020-11-19
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