Citrus canker type A is a serious disease caused by Xanthomonas citri subsp. citri (X. citri), which is responsible for severe losses to growers and to the citrus industry worldwide. To date, no canker-resistant citrus genotypes are available, and there is limited information regarding the molecular and genetic mechanisms involved in the early stages of the citrus canker development. Here, we present the CitrusKB knowledge base. This is the first in vivo interactome database for different citrus cultivars, and it was produced to provide a valuable resource of information on citrus and their interaction with the citrus canker bacterium X. citri. CitrusKB provides tools for a user-friendly web interface to let users search and analyse a large amount of information regarding eight citrus cultivars with distinct levels of susceptibility to the disease, with controls and infected plants at different stages of infection by the citrus canker bacterium X. citri. Currently, CitrusKB comprises a reference citrus genome and its transcriptome, expressed transcripts, pseudogenes and predicted genomic variations (SNPs and SSRs). The updating process will continue over time by the incorporation of novel annotations and analysis tools. We expect that CitrusKB may substantially contribute to the field of citrus genomics. CitrusKB is accessible at http://bioinfo.deinfo.uepg.br/citrus. Users can download all the generated raw sequences and generated datasets by this study from the CitrusKB website.

中文翻译：

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CitrusKB：柑橘属转录组和相互作用组的综合知识库。被柑橘黄单胞菌感染。不同感染阶段的柑橘

A型柑橘溃疡病是由柑橘黄单胞菌亚种引起的严重疾病。citri ( X. citri )，它对全球种植者和柑橘产业造成严重损失。迄今为止，没有抗溃疡病的柑橘基因型可用，并且关于柑橘溃疡病发展早期阶段所涉及的分子和遗传机制的信息有限。在这里，我们介绍了 CitrusKB 知识库。这是第一个不同柑橘栽培品种的体内相互作用组数据库，它的产生是为了提供有关柑橘及其与柑橘溃疡病细菌X. citri相互作用的宝贵信息资源. CitrusKB 为用户友好的 Web 界面提供工具，让用户可以搜索和分析有关该病易感性不同的八种柑橘品种的大量信息，以及在柑橘溃疡病细菌X感染不同阶段的对照和受感染植物. 柑橘. 目前，CitrusKB 包括参考柑橘基因组及其转录组、表达的转录本、假基因和预测的基因组变异（SNP 和 SSR）。通过结合新的注释和分析工具，更新过程将随着时间的推移而继续。我们预计 CitrusKB 可能会对柑橘基因组学领域做出重大贡献。CitrusKB 可在 http://bioinfo.deinfo.uepg.br/citrus 上访问。用户可以从 CitrusKB 网站下载本研究生成的所有原始序列和生成的数据集。