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Bridging a DNA Break to Leave a Poly(ADP-Ribose) Mark on Chromatin
Molecular Cell ( IF 14.5 ) Pub Date : 2020-11-19 , DOI: 10.1016/j.molcel.2020.10.044 Élise Rouleau-Turcotte , John M. Pascal
中文翻译:
桥接DNA断裂以在染色质上留下聚(ADP-核糖)标记
更新日期:2020-11-19
Molecular Cell ( IF 14.5 ) Pub Date : 2020-11-19 , DOI: 10.1016/j.molcel.2020.10.044 Élise Rouleau-Turcotte , John M. Pascal
Bilokapic at al. (2020) capture PARP2 and its accessory factor HPF1 bridging a DNA break between two nucleosomes, providing a captivating view of the context in which PARP2/HPF1 employ ADP-ribose protein modification to coordinate DNA repair and alter chromatin structure.
中文翻译:
桥接DNA断裂以在染色质上留下聚(ADP-核糖)标记
比洛克卡皮 (2020)捕获PARP2及其辅助因子HPF1桥接两个核小体之间的DNA断裂,提供了有关PARP2 / HPF1利用ADP-核糖蛋白修饰来协调DNA修复和改变染色质结构的背景的迷人观点。